Author

N. Saxena

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Animal Behavior & Cognition· 1 Bioengineering· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell type annotation· 2 Research Focus:gene regulatory network inference· 2 Assay:scRNA-seq· 2 Assay:ATAC-seq· 1 Assay:behavioral assay· 1

Frequent Co-Authors

S. Sen· 2 shared A. Barai· 1 shared A. Cherkasov· 1 shared A. Das· 1 shared A. K. Parra-Nunez· 1 shared A. Mukherjee· 1 shared B. Sun· 1 shared B. T. Dejene· 1 shared

Activity by Year

2017-2021 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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2 shared papersCell Biology

S. Sen

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Dynamic phase separation of the androgen receptor and its coactivators to regulate gene expression.

F. Zhang, S. Wong, J. Lee, S. Lingadahalli, C. Wells, N. Saxena, C. Sanchez, B. Sun, A. K. Parra-Nunez, N. Chan, J. M. Bui, Y. Wang, P. S. Rennie, N. A. Lack, A. Cherkasov, , N. Lallous

This study shows that androgen receptor (AR) and its co-activator MED1 form dynamic, AR-rich condensates at superenhancers in prostate cancer, which are crucial for oncogenic gene expression.

bioRxiv · Mar 27, 2021Cancer Biology

-actinin-4 drives invasiveness by regulating myosin IIB expression and myosin IIA localization

A. Barai, A. Mukherjee, A. Das, N. Saxena, S. Sen

This study shows ACTN4 regulates cancer cell invasiveness by controlling NMM IIB expression and NMM IIA localization during 3D invasion.

bioRxiv · Jan 12, 2021Cell Biology

Pre-metastatic niche drives breast cancer invasion by modulating MSC homing and CAF differentiation

N. Saxena, G. Bhardwaj, S. Jadhav, H. Zafar, S. Sen

The paper shows that pre-metastatic niche modulates MSC homing and CAF differentiation, promoting breast cancer invasion and metastasis.

bioRxiv · Jan 12, 2021 · PreprintCancer Biology

Gene Correction for SCID-X1 in Long-Term Hematopoietic Stem Cells

M. Pavel-Dinu, V. Wiebking, B. T. Dejene, W. Srifa, S. Mantri, C. Nicolas, C. Lee, G. Bao, E. J. Kildebeck, N. Punjya, C. Sindhu, M. A. Inlay, N. Saxena, S. S. DeRavin, H. Malech, , M. Porteus

This study corrects SCID-X1 in hematopoietic stem cells using CRISPR/Cas9, achieving high integration frequencies and low off-target effects, supporting clinical development.

bioRxiv · Aug 22, 2018Bioengineering

Odor source localization in complex visual environments by fruit flies

N. Saxena, D. Natesan, S. P. Sane

This study examines how fruit flies use visual and olfactory cues to locate odor sources in complex environments, revealing new strategies and behaviors in different airflow conditions.

bioRxiv · Aug 23, 2017Animal Behavior & Cognition