Tectonic Complex Impedes Diffusion through the Ciliary Transition Zone to Ensure Proper Sorting of Membrane Proteins
H. M. Truong, K. O. Cruz-Colon, J. Y. Martinez-Marquez, J. R. Willer, A. M. Travis, S. K. Biswas, W.-K. Lo, H. J. Bolz, J. N. Pearring
This study shows the tectonic complex physically impedes membrane protein diffusion through the transition zone to ensure proper sorting, leading to photoreceptor degeneration when disrupted.
bioRxiv · May 13, 2023Cell Biology