S. K. Lucas

Genomics and synthetic community experiments uncover the key metabolic roles of acetic acid bacteria in sourdough starter microbiomes

This paper uses genomics and synthetic community experiments to show that acetic acid bacteria (AAB) significantly influence sourdough starter function through metabolic diversity and strain-specific effects.

Developing and deploying an integrated workshop curriculum teaching computational skills for reproducible research

The paper develops a two-day workshop curriculum for teaching reproducible research using R, Unix, git, and GitHub, addressing content overload and integration challenges in existing curricula.

Dual oxic-anoxic co-culture enables direct study of host-anaerobe interactions at the airway epithelial interface

The paper introduces a dual oxic-anoxic co-culture system to study host-anaerobe interactions in airway epithelial cells and shows its utility in revealing mucus degradation and transcriptional responses to anaerobe infection.

Bioorthogonal non-canonical amino acid tagging reveals translationally active subpopulations of the cystic fibrosis lung microbiota

The paper uses BONCAT to identify translationally active bacterial subpopulations in CF lung microbiota, finding only 12-18% of cells are actively translating.

16S rRNA Gene Sequencing Reveals Site-Specific Signatures Of The Upper And Lower Airways Of Cystic Fibrosis Patients

This study compares the microbiomes of sinus mucus and lung sputum from CF patients, finding distinct community structures and functional profiles between upper and lower airways.