Author

S. K. Wyman

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Cancer Biology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 3 Assay:CRISPR screen· 2 Research Focus:gene regulatory network inference· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:plant (other)· 1 Organism:Xenopus· 1

Frequent Co-Authors

J. Corn· 2 shared J. Shin· 2 shared A. S. Wang· 1 shared A. Schultink· 1 shared A. T. Iavarone· 1 shared B. G. Gowen· 1 shared B. J. Staskawicz· 1 shared B. K. Gill· 1 shared

Activity by Year

2018-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersCell Biology

J. Corn

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

CRISPR-Cas9-mediated knockout of CYP79D1 and CYP79D2 in cassava attenuates toxic cyanogen production

M. A. Gomez, K. C. Berkoff, B. K. Gill, A. T. Iavarone, S. E. Lieberman, J. M. Ma, A. Schultink, S. K. Wyman, R. D. Chauhan, N. J. Taylor, B. J. Staskawicz, M.-J. Cho, D. S. Rokhsar, J. B. Lyons

This study uses CRISPR-Cas9 to knockout CYP79D1 and CYP79D2 in cassava, reducing cyanide production and improving food safety.

bioRxiv · Oct 8, 2021Plant Biology

Genome editing to model and reverse a prevalent mutation associated with myeloproliferative neoplasms

R. Baik, S. K. Wyman, S. Kabir, J. E. Corn

This study uses CRISPR-Cas9 to model and reverse the JAK2 V617F mutation in human hematopoietic cells, revealing subtle phenotypes not seen with transgenic overexpression.

bioRxiv · Nov 26, 2019Cancer Biology

The histone chaperone FACT induces Cas9 multi-turnover behavior and modifies genome manipulation in human cells

A. S. Wang, L. Chen, R. A. Wu, C. D. Richardson, B. G. Gowen, K. R. Kazane, J. T. Vu, S. K. Wyman, J. Shin, J. C. Walter, J. Corn

This study identifies FACT as a factor that influences Cas9 turnover and genome editing efficiency in human cells.

bioRxiv · Jul 23, 2019Cell Biology

Controlled cycling and quiescence enables homology directed repair in engraftment-enriched adult hematopoietic stem and progenitor cells

J. Shin, S. K. Wyman, M. A. DeWitt, N. L. Bray, J. Vu, J. Corn

This study shows that quiescent hematopoietic stem and progenitor cells (HSPCs) predominantly use error-prone repair, while cycling cells use both error-prone and accurate repair, and presents a strategy to enhance homology-directed repair (HDR) by cycling HSPCs.

bioRxiv · Apr 13, 2018Cell Biology