A salt bridge-mediated resistance mechanism to FtsZ inhibitor PC190723 revealed by a cell-based screen
A. K. Sharma, S. M. Poddar, J. Chakraborty, B. S. Nayak, S. Kalathil, N. Mitra, P. Gayathri, R. SRINIVASAN
This paper develops a cell-based assay to screen for FtsZ inhibitors and identifies a salt bridge-mediated resistance mechanism to PC190723 in Helicobacter pylori FtsZ.
bioRxiv · Apr 6, 2022Cell Biology