Nix induced mitochondrial fission, mitophagy, and myocyte insulin resistance are abrogated by PKA phosphorylation.
S. C. da Silva Rosa, M. D. Martens, J. T. Field, L. Nguyen, S. Kereliuk, Y. Hai, D. Chapman, W. Diehl-Jones, M. Aliani, A. R. West, J. Thliveris, S. Ghavami, C. Rampitsch, V. W. Dolinsky, J. Gordon
The paper shows that Nix-induced mitochondrial fission, mitophagy, and insulin resistance in myocytes are reversed by PKA phosphorylation.
bioRxiv · Feb 20, 2020Cell Biology