Author

S. Koester

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 7 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 7 Organism:human· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:chromatin & epigenetic regulation· 2 Research Focus:protein folding & dynamics· 2 Research Focus:cell type annotation· 1 Assay:cryo-EM· 1 Research Focus:differential expression· 1

Frequent Co-Authors

C. Lorenz· 4 shared J. Kraxner· 4 shared A. V. Schepers· 3 shared H. Witt· 2 shared J. Forsting· 2 shared S. Klumpp· 2 shared A. A. Chouaib· 1 shared A. H. Shaib· 1 shared

Activity by Year

2019-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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4 shared papersBiophysics

C. Lorenz

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

Vimentin filaments integrate low complexity domains in a highly complex helical structure

M. Eibauer, M. S. Weber, R. Kronenberg-Tenga, C. T. Beales, R. Boujemaa-Paterski, Y. Turgay, S. Sivagurunathan, J. Kraxner, S. Koester, R. D. Goldman, O. Medalia

This study determines the 3D structure of vimentin intermediate filaments, revealing how disordered domains contribute to their mechanical properties.

bioRxiv · May 22, 2023Biochemistry

Visualizing proteins by expansion microscopy

A. H. Shaib, A. A. Chouaib, R. Chowdhury, D. Mihaylov, C. Zhang, V. Imani, S. V. Georgiev, N. Mougios, M. Monga, S. Reshetniak, T. Mimoso, H. Chen, P. Fatehbasharzad, D. Crzan, N. Alawar, , S. Rizzoli

This paper introduces ONE microscopy, a technique that enables nanoscale imaging of single proteins and molecular complexes, revealing structural details in cells and disease samples.

bioRxiv · Aug 3, 2022Biophysics

Multiscale mechanics and temporal evolution of vimentin intermediate filament networks

A. V. Schepers, C. Lorenz, P. Nietmann, A. V. Janshoff, S. Klumpp, S. Koester

This study investigates the mechanics and temporal evolution of vimentin intermediate filament networks using multiscale approaches and finds that hydrophobic and electrostatic forces influence network stability and reorganization.

bioRxiv · Jan 30, 2021Biophysics

Post-Translational Modifications Soften Vimentin Intermediate Filaments

J. Kraxner, C. Lorenz, J. Menzel, I. Parfentev, I. Silbern, M. Denz, H. Urlaub, B. Schwappach, S. Koester

This study investigates how post-translational modifications, specifically phosphorylation and 14-3-3 binding, affect the mechanical properties of vimentin intermediate filaments.

bioRxiv · Jun 5, 2020Biophysics

Tuning Intermediate Filament Mechanics by Variation of pH and Ion Charges

A. V. Schepers, C. Lorenz, S. Koester

This study investigates how pH and ion concentration affect the mechanical properties of vimentin intermediate filaments using optical trapping and simulations.

bioRxiv · Jun 4, 2020Biophysics

Programmed transport and release of nanoscale cargo by immune cells

D. Meyer, S. Telele, A. Zelena, E. Neubert, R. Nissler, F. Mann, L. Erpenbeck, S. Koester, S. Kruss

This study programs human neutrophils to transport and release nanoscale cargo via NETosis, demonstrating controlled delivery of functional nanomaterials.

Nanoscale · Jan 1, 2020Peer-reviewedBiophysics

Vimentin intermediate filaments undergo irreversible conformational changes during cyclic loading

J. Forsting, J. Kraxner, H. Witt, A. Janshoff, S. Koester

This study shows vimentin intermediate filaments undergo irreversible conformational changes under cyclic loading, introducing a third state to explain their mechanical behavior.

bioRxiv · Sep 25, 2019Biophysics

Lateral Subunit Coupling Determines Intermediate Filament Mechanics

C. Lorenz, J. Forsting, A. V. Schepers, J. Kraxner, S. Bauch, H. Witt, S. Klumpp, S. Koester

This study compares the mechanical properties of keratin and vimentin filaments, showing vimentin's mechanics depend on ionic strength and involve strong lateral subunit coupling.

bioRxiv · Jun 19, 2019Biophysics