Author

S. L. Spitalnik

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Organism:mouse· 3 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

A. D'Alessandro· 3 shared E. A. Hod· 3 shared J. C. Zimring· 3 shared K. E. Hudson· 2 shared M. Dzieciatkowska· 2 shared T. Thomas· 2 shared A. Hay· 1 shared A. M. Hay· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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3 shared papersBiochemistry

A. D'Alessandro

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Author profile →

3 papers

Recent·Most cited

Biological and Genetic Determinants of Glycolysis: Phosphofructokinase Isoforms Boost Energy Status of Stored Red Blood Cells and Transfusion Outcomes

T. Nemkov, D. Stephenson, E. J. Earley, G. R. Keele, A. Hay, A. M. Key, Z. Haiman, C. Erickson, M. Dzieciatkowska, J. A. Reisz, A. Moore, M. Stone, X. Deng, S. Kleinman, S. L. Spitalnik, , A. D'Alessandro

The paper identifies genetic polymorphisms and metabolite levels in stored red blood cells that correlate with hemolysis and transfusion outcomes.

Cell Metabolism · Sep 1, 2024Peer-reviewedBiochemistry

Reticulocytes in donor RBC units enhance RBC alloimmunization

T. Thomas, A. Qiu, C. Y. Kim, D. E. Gordy, A. Miller, M. Tredicine, M. Dzieciatkowska, F. Dei Zotti, E. A. Hod, A. D'Alessandro, J. C. Zimring, S. L. Spitalnik, K. E. Hudson

This study shows that reticulocytes in donor RBC units increase alloimmunization rates in mice by enhancing alloantibody levels and proinflammatory responses.

bioRxiv · Jan 25, 2023 · PreprintImmunology

Hematologic and systemic metabolic alterations due to Mediterranean type II G6PD deficiency in a novel murine model

A. D'Alessandro, H. L. Howie, A. M. Hay, K. H. Dziewulska, B. Brown, M. J. Wither, M. Karafin, E. F. Stone, S. L. Spitalnik, E. A. Hod, R. O. Francis, X. Fu, T. Thomas, J. C. Zimring

This study creates a novel murine model of severe G6PD deficiency by introducing a human mutation, revealing metabolic alterations and hemolytic sequelae similar to humans.

bioRxiv · May 31, 2021 · PreprintBiochemistry