S. Leptihn

In vitro and in vivo evaluation of the biofilm-degrading Pseudomonas phage Motto, as a candidate for phage therapy

This paper evaluates the Pseudomonas phage Motto for its ability to degrade biofilms and treat P. aeruginosa infections in vitro and in vivo, finding it effective against biofilm-producing isolates and safe in human cell lines.

From motor protein to toxin: Mutations in the zonula occludens toxin (Zot) of Vibrio cholerae phage CTXΦ suggest a loss of phage assembly function

The paper investigates mutations in the Zot toxin of Vibrio cholerae phage CTXΦ, showing that these mutations impair phage assembly and suggest a shift in Zot's function to an auxiliary toxin.

Phage-antibiotic combinations to control Pseudomonas aeruginosa-Candida two-species biofilms

This study evaluates phage-antibiotic/antifungal combinations against single- and dual-species biofilms of P. aeruginosa and C. albicans, finding some synergistic effects but limited efficacy against dual-species biofilms.

A Lysozyme Murein Hydrolase with Broad-spectrum Antibacterial Activity from Enterobacter Phage myPSH1140

This study characterizes Gp105, a lysozyme murein hydrolase from Enterobacter phage myPSH1140, showing broad-spectrum antibacterial activity against Gram-negative pathogens.

A multiwell-plate Caenorhabditis elegans assay for assessing the therapeutic potential of Bacteriophages against Clinical Pathogens

This paper develops a C. elegans assay to evaluate phage efficacy against clinical pathogens, showing improved survival rates with phage treatment.

Correlation of mitochondrial TOM core complex stop-and-go and open-closed channel dynamics

The paper examines how lateral diffusion of mitochondrial TOM-CC proteins correlates with channel permeability states and mechanosensitive properties.

Phage Resistance Mechanisms Increase Colistin Sensitivity in Acinetobacter baumannii

This study shows that phage resistance mechanisms in A. baumannii reduce colistin resistance by altering bacterial envelope structure, increasing antibiotic sensitivity.

Characterisation of bacteriophage JD419, a Staphylococcal phage with an unusual morphology and broad host range

This paper characterizes bacteriophage JD419, which has a broad host range and retains lytic activity under various conditions, and reports its genome lacking virulence or antibiotic resistance genes.

BacAnt: A Combination Annotation Server for Bacterial DNA Sequences to Identify Antibiotic Resistance Genes, Integrons, and Transposable Elements.

BacAnt is a webserver that simultaneously annotates antibiotic resistance genes, integrons, and transposable elements in bacterial DNA sequences, generating automated genbank files.

Dissemination of carbapenem-resistance and plasmids encoding carbapenemases in Gram-negative bacteria isolated from India

This study examines carbapenem resistance and plasmid-borne carbapenemase genes in Gram-negative bacteria from Tamil Nadu, India, finding high resistance rates and plasmid transfer capabilities.