Coupled small molecules target RNA interference and JAK/STAT signaling to reduce Zika virus infection in Aedes aegypti
C. E. Trammell, G. Ramirez, I. Sanchez-Vargas, S. Luckhart, R. Perera, A. G. Goodman
This study shows that repurposed small molecules activate both RNA interference and JAK/STAT antiviral pathways in Aedes aegypti, significantly reducing Zika virus levels.
bioRxiv · Aug 23, 2021Microbiology