Author

S. MacDonald

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Cancer Biology· 1 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Approach:biophysical modeling· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Organism:plant (other)· 1

Frequent Co-Authors

C. Campa· 1 shared C. de Souza· 1 shared C. R. Safinya· 1 shared E. Hirsch· 1 shared J. Colicchio· 1 shared J. Crowe· 1 shared J. K. Kelly· 1 shared J. Lee· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperCancer Biology

C. Campa

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Lipids with negative spontaneous curvature decrease the solubility of the cancer drug paclitaxel in liposomes

V. M. Steffes, S. MacDonald, J. Crowe, M. Murali, K. K. Ewert, Y. Li, C. R. Safinya

This study shows that lipids with negative spontaneous curvature, like DOPE and GMO, reduce paclitaxel solubility in liposomes, making them unsuitable for drug delivery.

bioRxiv · Oct 18, 2023Biophysics

Predicting evolutionary change at the DNA level in a natural Mimulus population

P. Monnahan, J. Colicchio, L. Fishman, S. Macdonald, J. K. Kelly

The paper predicts DNA-level evolutionary change in Mimulus guttatus by calibrating population genetic models with fitness estimates and SNP frequency shifts.

bioRxiv · Jun 23, 2020Evolutionary Biology

Activation of Rab11a and endocytosis by Phosphatidylinositol 4-kinase III beta promotes oncogenic signaling in breast cancer

S. MacDonald, K. Harding, P. Bilodeau, C. de Souza, C. Campa, E. Hirsch, R. Auer, J. Lee

This study shows that PI4KIIIβ promotes breast cancer by regulating endocytic kinetics and Rab11a-mediated signaling through its interaction with Rab11a, independent of its kinase activity.

bioRxiv · Feb 10, 2020 · PreprintCancer Biology