Author

J. Crowe

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Biophysics· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:mouse· 2 Research Focus:clustering· 1 Research Focus:drug response / drug discovery· 1 Approach:machine learning (classical)· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

A. Tarafdar· 2 shared F. E. Lumb· 2 shared J. Doonan· 2 shared M. A. Pineda· 2 shared M. M. Harnett· 2 shared P. A. Hoskisson· 2 shared W. Harnett· 2 shared A. C. Marriott· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersImmunology

A. Tarafdar

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Lipids with negative spontaneous curvature decrease the solubility of the cancer drug paclitaxel in liposomes

V. M. Steffes, S. MacDonald, J. Crowe, M. Murali, K. K. Ewert, Y. Li, C. R. Safinya

This study shows that lipids with negative spontaneous curvature, like DOPE and GMO, reduce paclitaxel solubility in liposomes, making them unsuitable for drug delivery.

bioRxiv · Oct 18, 2023Biophysics

Sequential delivery of LAIV and SARS-CoV-2 in the ferret model can reduce SARS-CoV-2 shedding and does not result in enhanced lung pathology.

K. A. Ryan, K. E. Schewe, J. Crowe, S. A. Fotheringham, Y. Hall, R. Humphreys, A. C. Marriott, J. Paterson, E. Rayner, F. J. Salguero, R. J. Watson, C. J. Whittaker, M. W. Carroll, O. Dibben

This study shows that administering LAIV before or after SARS-CoV-2 infection in ferrets does not worsen disease and may reduce viral shedding.

bioRxiv · Feb 1, 2021Microbiology

Parasitic worm-derived ES-62 promotes health- and life-span in high calorie diet-fed mice

J. Crowe, F. E. Lumb, J. Doonan, M. Broussard, A. Tarafdar, M. A. Pineda, C. Landabaso, L. Mulvey, P. A. Hoskisson, S. Babayan, C. Selman, W. Harnett, M. M. Harnett

ES-62, a parasitic worm-derived immunomodulator, improves healthspan and extends lifespan in male mice fed a high-calorie diet.

bioRxiv · Jun 22, 2019 · PreprintImmunology

The parasitic worm product ES-62 normalises the gut microbiota/bone marrow axis in inflammatory arthritis

J. Doonan, A. Tarafdar, M. A. Pineda, F. E. Lumb, J. Crowe, A. M. Khan, P. A. Hoskisson, M. M. Harnett, W. Harnett

This study shows that the parasitic worm product ES-62 reduces joint inflammation in arthritis by normalising gut microbiota and preserving intestinal barrier integrity without requiring live helminth infection.

bioRxiv · Nov 2, 2018Immunology