Author

S. N. Loftus

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Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

A. M. Victory· 1 shared B. Klein· 1 shared B. Xu· 1 shared C. C. Berthier· 1 shared C. J. Dobry· 1 shared F. Ma· 1 shared G. A. Hile· 1 shared J. E. Gudjonsson· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

A. M. Victory

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1 paper

Recent·Most cited

Epidermal ZBP1 stabilizes mitochondrial Z-DNA to drive UV-induced IFN signaling in autoimmune photosensitivity

B. Klein, M. B. Reynolds, B. Xu, M. Gharaee-Kermani, Y. Gao, C. C. Berthier, S. Henning, S. N. Loftus, K. E. McNeely, A. M. Victory, C. J. Dobry, G. A. Hile, F. Ma, J. L. Turnier, J. E. Gudjonsson, , J. M. Kahlenberg

The paper identifies ZBP1 and mitochondrial Z-DNA as drivers of autoimmune photosensitivity through cGAS-STING activation in response to UVB.

Science Immunology · Mar 7, 2025Peer-reviewedImmunology