Author

M. B. Reynolds

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Assay:proteomics· 3 Research Focus:cell signaling & trafficking· 2 Assay:metabolomics· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

M. X. O'Riordan· 3 shared B. C. Michmerhuizen· 2 shared B. Klein· 2 shared C. A. Lyssiotis· 2 shared J. M. Kahlenberg· 2 shared L. Zhang· 2 shared A. M. Victory· 1 shared A.-L. E. Lawrence· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersImmunology

M. X. O'Riordan

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3 papers

Recent·Most cited

Epidermal ZBP1 stabilizes mitochondrial Z-DNA to drive UV-induced IFN signaling in autoimmune photosensitivity

B. Klein, M. B. Reynolds, B. Xu, M. Gharaee-Kermani, Y. Gao, C. C. Berthier, S. Henning, S. N. Loftus, K. E. McNeely, A. M. Victory, C. J. Dobry, G. A. Hile, F. Ma, J. L. Turnier, J. E. Gudjonsson, , J. M. Kahlenberg

The paper identifies ZBP1 and mitochondrial Z-DNA as drivers of autoimmune photosensitivity through cGAS-STING activation in response to UVB.

Science Immunology · Mar 7, 2025Peer-reviewedImmunology

Type I interferon governs immunometabolic checkpoints that coordinate inflammation during Staphylococcal infection

M. B. Reynolds, B. Klein, M. J. McFadden, N. K. Judge, H. E. Navarrete, B. C. Michmerhuizen, D. Awad, T. L. Schultz, P. W. Harms, L. Zhang, T. R. O'Meara, J. Z. Sexton, C. A. Lyssiotis, J. M. Kahlenberg, M. X. O'Riordan

This paper shows type I interferon coordinates immunometabolic checkpoints during Staphylococcal infection by regulating metabolic and inflammatory programs in macrophages.

bioRxiv · Jan 10, 2024 · PreprintImmunology

Cardiolipin coordinates inflammatory metabolic reprogramming through regulation of Complex II assembly and stability

M. B. Reynolds, H. S. Hong, B. C. Michmerhuizen, A.-L. E. Lawrence, L. Zhang, J. S. Knight, C. A. Lyssiotis, B. H. Abuaita, M. X. O'Riordan

The paper shows cardiolipin regulates Complex II assembly and stability in macrophages, linking it to inflammatory metabolic reprogramming.

bioRxiv · Jul 27, 2022 · PreprintImmunology