Author

C. C. Berthier

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Approach:experimental assay· 4 Organism:human· 4 Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Assay:scRNA-seq· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1

Frequent Co-Authors

M. Kretzler· 3 shared A. Arazi· 2 shared C. Putterman· 2 shared D. L. Kamen· 2 shared D. Wofsy· 2 shared E. S. Woodle· 2 shared F. Payan-Schober· 2 shared K. C. Kalunian· 2 shared

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2018-2025 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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3 shared papersImmunology

M. Kretzler

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4 papers

Recent·Most cited

Epidermal ZBP1 stabilizes mitochondrial Z-DNA to drive UV-induced IFN signaling in autoimmune photosensitivity

B. Klein, M. B. Reynolds, B. Xu, M. Gharaee-Kermani, Y. Gao, C. C. Berthier, S. Henning, S. N. Loftus, K. E. McNeely, A. M. Victory, C. J. Dobry, G. A. Hile, F. Ma, J. L. Turnier, J. E. Gudjonsson, , J. M. Kahlenberg

The paper identifies ZBP1 and mitochondrial Z-DNA as drivers of autoimmune photosensitivity through cGAS-STING activation in response to UVB.

Science Immunology · Mar 7, 2025Peer-reviewedImmunology

Blood immunophenotyping identifies distinct kidney histopathology and outcomes in patients with lupus nephritis

A. Horisberger, A. Griffith, J. Keegan, A. Arazi, J. Pulford, E. Murzin, K. Howard, B. Hancock, A. Fava, T. Sasaki, T. Ghosh, J. Inamo, R. Beuschel, Y. Cao, K. Preisinger, , Accelerating Medicines Pa

The paper identifies three immunologically distinct groups in lupus nephritis patients based on blood immunophenotyping, correlating with histopathology, treatment response, and renal outcomes.

bioRxiv · Jan 14, 2024Immunology

Urine single cell RNA-sequencing in focal segmental glomerulosclerosis reveals inflammatory signatures in immune cells and podocytes

K. Z. Latt, J. Heymann, J. H. Jessee, A. Z. Rosenberg, C. C. Berthier, S. Eddy, T. Yoshida, Y. Zhao, V. Chen, G. W. Nelson, M. Cam, P. Kumar, M. Mehta, M. C. Kelly, M. Kretzler, , J. B. Kopp

This study uses urine single cell RNA-sequencing to identify inflammatory signatures in immune cells and podocytes in FSGS, suggesting potential for non-invasive diagnosis and biomarker discovery.

bioRxiv · Oct 18, 2020Immunology

The immune cell landscape in kidneys of lupus nephritis patients

A. Arazi, D. A. Rao, C. C. Berthier, A. Davidson, Y. Liu, P. J. Hoover, A. Chicoine, T. M. Eisenhaure, A. H. Jonsson, S. Li, D. J. Lieb, E. P. Browne, A. Noma, D. Sutherby, S. Steelman, , B. Diamond

This study uses single-cell RNA-seq to analyze immune cell subsets in lupus nephritis kidneys, identifying pro-inflammatory and resolving responses and potential therapeutic targets.

bioRxiv · Jul 7, 2018Immunology