Author

S. Ohira

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 2

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Research Focus:cell signaling & trafficking· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Inoue· 1 shared A. Ogawa· 1 shared F.-Y. Wei· 1 shared J. Nakabayashi· 1 shared K. Iwato· 1 shared K. Tsumura· 1 shared M. Nishida· 1 shared M. Tanabe· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperPharmacology & Toxicology

A. Inoue

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2 papers

Recent·Most cited

A novel in silico scaffold-hopping method for drug repositioning in rare and intractable diseases

M. Tanabe, R. Sakate, J. Nakabayashi, K. Tsumura, S. Ohira, K. Iwato, T. Kimura

This paper introduces a novel in silico scaffold-hopping method for drug repositioning, identifying 144 compounds with potential new therapeutic applications for rare diseases.

bioRxiv · Jul 3, 2023 · PreprintPharmacology & Toxicology

Activation of the urotensin-II receptor by anti-COVID-19 drug remdesivir induces cardiomyocyte dysfunction

F.-Y. Wei, A. Inoue, A. Ogawa, S. Ohira, T. Ikuta, Y. Kato, S. Yanagida, Y. Ishii, Y. Kanda, M. Nishida

This study identifies remdesivir as a selective agonist of the urotensin-II receptor, linking its cardiotoxicity to receptor activation and genetic variants.

bioRxiv · Aug 8, 2022 · PreprintPharmacology & Toxicology