Author

S. P. M. Venkata

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Pharmacology & Toxicology· 1

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Research Focus:cell signaling & trafficking· 1 Approach:mechanistic / dynamical model· 1

Frequent Co-Authors

A. Smrcka· 1 shared C. W. Dessauer· 1 shared E. Mukhaleva· 1 shared N. R. Chandan· 1 shared N. Vaidehi· 1 shared S. Abraham· 1 shared T. Lefevre· 1 shared W. Wei· 1 shared

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2023-2023 · peak 1/yr

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9 top collaborators · 36 mutual co-author links

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1 shared paperPharmacology & Toxicology

A. Smrcka

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1 paper

Recent·Most cited

Pharmacology & ToxicologybioRxivMar 10, 2023

Stablization of Interdomain Interactions in G protein αi Subunits Determines Gαi Subtype Signaling Specificity

T. Lefevre, W. Wei, E. Mukhaleva…·A. Smrcka

This study identifies an amino acid difference that stabilizes interdomain interactions in Gi1 but not Gi2, leading to differences in effector activation and signaling specificity.

DOI 10.1016/j.jbc.2024.107211

mechanistic / dynamical modelcell signaling & trafficking

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