T. Lefevre

Mosquito aging modulates the development, virulence and transmission potential of pathogens

This study shows that older mosquitoes transmit malaria less efficiently but live longer when infected, affecting transmission dynamics.

The paradox of plant preference: the malaria vectors Anopheles gambiae and Anopheles coluzzii select suboptimal food sources for their survival and reproduction

This study shows that malaria mosquitoes prefer plants that are less nutritious and harmful to their survival and reproduction.

Stablization of Interdomain Interactions in G protein αi Subunits Determines Gαi Subtype Signaling Specificity

This study identifies an amino acid difference that stabilizes interdomain interactions in Gi1 but not Gi2, leading to differences in effector activation and signaling specificity.

Multiple hosts, multiple impacts: the role of vertebrate host diversity in shaping mosquito life history and pathogen transmission

This study examines how different vertebrate blood meal sources affect mosquito fitness and malaria parasite transmission, finding that blood meal type significantly impacts mosquito traits but not parasite development.

Intervention reducing malaria parasite load in vector mosquitoes: no impact on Plasmodium falciparum extrinsic incubation period and the survival of Anopheles gambiae

This study tests whether reducing Plasmodium falciparum parasite load in Anopheles gambiae mosquitoes affects their survival or the parasite's extrinsic incubation period, finding no impact on these key transmission parameters.

Antimalarials in mosquitoes overcome Anopheles and Plasmodium resistance to malaria control strategies

This paper demonstrates that antimalarial drugs can block malaria transmission by targeting mosquitoes, remaining effective against resistant strains of both mosquitoes and parasites.

A mating-induced reproductive gene promotes Anopheles tolerance to Plasmodium falciparum infection

The paper shows that mating-induced gene MISO in Anopheles mosquitoes protects females from fecundity costs of Plasmodium falciparum infection without affecting parasite development.

Opening Pandora’s Box: Distribution of Plasmodium gametocytes in bloodstream

The paper shows that gametocyte distribution varies within vertebrate hosts, leading to uncertainty in transmission potential estimates from single blood samples.

High Plasmodium infection intensity in naturally infected malaria vectors in Africa

The paper estimates parasite exposure in naturally infected malaria vectors in Burkina Faso and finds it is higher than previous estimates, with a strong link between mosquito infection and human parasite prevalence.

Field evidence for manipulation of mosquito host selection by the human malaria parasite, Plasmodium falciparum

The paper shows that Plasmodium falciparum increases mosquito anthropophagy in infectious females, enhancing parasite transmission.

Can malaria parasites manipulate the odour-mediated host preference of their mosquito vectors?

This study investigates whether malaria parasites manipulate mosquito host choice toward suitable hosts, finding no effect on activation rate or odour preference in infected mosquitoes.