Author

S. P. Mackessy

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:clustering· 1 Approach:comparative / phylogenetic analysis· 1 Approach:deep learning· 1

Frequent Co-Authors

C. M. Modahl· 2 shared A. J. Saviola· 1 shared B. Lomonte· 1 shared B. T. Martin· 1 shared B. W. Perry· 1 shared C. F. Smith· 1 shared C. Vaz· 1 shared D. Ceja-Galindo· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersBiochemistry

C. M. Modahl

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Author profile →

3 papers

Recent·Most cited

ASSESSING TARGET SPECIFICITY OF THE SMALL MOLECULE INHIBITOR MARIMASTAT TO SNAKE VENOM TOXINS: A NOVEL APPLICATION OF THERMAL PROTEOME PROFILING

C. F. Smith, C. M. Modahl, D. Ceja-Galindo, K. Y. Larson, S. P. Maroney, L. Bahrabadi, N. P. Brandehoff, B. W. Perry, M. C. McCabe, D. Petras, B. Lomonte, J. J. Calvete, T. A. Castoe, S. P. Mackessy, K. C. Hansen, A. J. Saviola

This study uses Thermal Proteome Profiling and PISA to assess marimastat's specificity against snake venom toxins, identifying its targets and interactions with specific proteoforms.

bioRxiv · Oct 25, 2023Biochemistry

Distinct regulatory networks control toxin gene expression in elapid and viperid snakes

C. M. Modahl, X. Han, J. van Thiel, C. Vaz, N. L. Dunstan, S. Frietze, T. N. W. Jackson, S. P. Mackessy, R. M. Kini

This study compares regulatory networks of toxin gene expression in elapid and viperid snakes, finding distinct histone methylation, transcription factor, and microRNA regulation between the families.

bioRxiv · Feb 13, 2023Evolutionary Biology

Relictual Hybridization and Biogeography of Massasauga Rattlesnakes (Sistrurus spp.)

B. T. Martin, M. R. Douglas, T. K. Chafin, J. S. Placyk, S. P. Mackessy, J. T. Briggler, M. E. Douglas

This study examines hybridization and biogeography in Massasauga rattlesnakes using ddRAD sequencing, revealing population structure and historical range dynamics shaped by climate change.

bioRxiv · Aug 29, 2022 · PreprintEvolutionary Biology