Author

T. A. Castoe

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:whole-genome sequencing· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

B. W. Perry· 2 shared A. J. Saviola· 1 shared B. Lomonte· 1 shared B. Panesar· 1 shared B. S. Chang· 1 shared B. Zhong· 1 shared C. F. Smith· 1 shared C. M. Modahl· 1 shared

Activity by Year

2017-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersBiochemistry

B. W. Perry

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

ASSESSING TARGET SPECIFICITY OF THE SMALL MOLECULE INHIBITOR MARIMASTAT TO SNAKE VENOM TOXINS: A NOVEL APPLICATION OF THERMAL PROTEOME PROFILING

C. F. Smith, C. M. Modahl, D. Ceja-Galindo, K. Y. Larson, S. P. Maroney, L. Bahrabadi, N. P. Brandehoff, B. W. Perry, M. C. McCabe, D. Petras, B. Lomonte, J. J. Calvete, T. A. Castoe, S. P. Mackessy, K. C. Hansen, A. J. Saviola

This study uses Thermal Proteome Profiling and PISA to assess marimastat's specificity against snake venom toxins, identifying its targets and interactions with specific proteoforms.

bioRxiv · Oct 25, 2023Biochemistry

Population genomic analyses of schistosome parasites highlight critical challenges facing end-game elimination efforts

J. A. Shortt, L. E. Timm, N. R. Hales, Z. L. Nikolakis, D. R. Schield, B. W. Perry, Y. Liu, B. Zhong, T. A. Castoe, E. J. Carlton, D. D. Pollock

The paper identifies local parasite reservoirs and persistent infections in humans as key barriers to schistosomiasis elimination despite treatment efforts.

bioRxiv · Apr 30, 2020Evolutionary Biology

Targeted capture of complete coding regions across divergent species

R. Schott, B. Panesar, D. C. Card, M. Preston, T. A. Castoe, B. S. Chang

This paper develops a targeted capture method to recover complete coding regions across divergent species, enabling large-scale comparative studies of molecular evolution and function.

bioRxiv · Jan 9, 2017Evolutionary Biology