Author

S. Pospisilova

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 5

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Assay:bulk RNA-seq· 3 Research Focus:cell type annotation· 3 Organism:human· 3 Research Focus:differential expression· 2 Approach:benchmark study· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

B. Tichy· 2 shared C. Sternberg· 2 shared D. Lindner· 2 shared F. Sternberg· 2 shared H. A. Neubauer· 2 shared J. L. Persson· 2 shared K. Plevova· 2 shared K. Trachtova· 2 shared

Activity by Year

2020-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersCancer Biology

B. Tichy

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Cell-autonomous GP130 activation suppresses prostate cancer development via STAT3/ARF/p53-driven senescence and confers an immune-active tumor microenvironment

C. Sternberg, T. Limberger, M. Raigel, K. Trachtova, M. Schlederer, D. Lindner, P. Kodajova, J. Yang, R. Ziegler, H. A. Neubauer, S. Dey, T. Redmer, S. Stoiber, V. Hejret, B. Tichy, , L. Kenner

This study shows that activating GP130 in prostate epithelial cells suppresses tumor growth through senescence and immune activation, suggesting a new therapeutic approach.

bioRxiv · Feb 11, 2024 · PreprintCancer Biology

JUN mediates senescence and immune cell recruitment to prevent prostate cancer progression

T. Redmer, M. Raigel, C. Sternberg, R. Ziegler, C. Probst, D. Lindner, A. Aufinger, T. Limberger, K. Trachtova, P. Kodajova, S. Hoegler, M. Schlederer, S. Stoiber, M. Oberhuber, M. Bolis, , L. Kenner

This study shows JUN suppresses prostate cancer progression by inducing senescence and immune cell recruitment, with JUN depletion accelerating tumor growth.

bioRxiv · Nov 29, 2023 · PreprintCancer Biology

The Minimal Dataset for Cancer of the 1+Million Genomes Initiative

M. Riba, C. Sala, A. Culhane, A. Flobak, A. Patocs, K. Boye, K. Plevova, S. Pospisilova, G. Gandolfi, M. Morelli, G. Bucci, A. Edsjo, U. Lassen, F. Al-Shahrour, N. Lopez-Bigas, , G. Tonon

The paper develops a standardized data model for cancer genomics to enable interoperable data sharing across countries.

bioRxiv · Oct 7, 2023 · PreprintCancer Biology

Mobile retroelements induced by hypomethylating agents are restricted to transpose in myeloid malignancies

S. Pavlova, M. Krzyzankova, A. Volakhava, A. Smirnova, T. Grigoreva, Z. Jaskova, H. Synackova, D. Wahl, M. Bohunova, L. Cervinek, S. Pospisilova, I. Mamedov, K. Plevova

The paper investigates whether hypomethylating agents induce retroelement activity and somatic retrotranspositions in myeloid malignancies but finds no de novo retrotransposition events.

bioRxiv · Jul 30, 2023 · PreprintCancer Biology

Lyn controls chemotaxis and motility of CLL cells via phosphorylation of ROR1.

Z. Dave, O. Vondalova-Blanarova, S. Cada, P. Janovska, N. Zezula, M. Behal, K. Hanakova, S. R. Ganjani, P. Krejci, K. Gmöryöva, H. Peschelova, M. Smida, Z. Zdrahal, S. Pavlova, J. Kotaskova, , V. Bryja

This study shows Lyn phosphorylates ROR1, affecting its surface levels and migratory properties in CLL cells, linking BCR and ROR1 signaling.

bioRxiv · May 29, 2020Cancer Biology