Author

K. Hanakova

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 4 Research Focus:cell signaling & trafficking· 3 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

Z. Zdrahal· 4 shared V. Bryja· 3 shared D. Potesil· 2 shared L. Cajanek· 2 shared O. Bernatik· 2 shared B.-K. Koo· 1 shared D. Vyslouzil· 1 shared E. Janssen· 1 shared

Activity by Year

2019-2020 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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4 shared papersCancer Biology

Z. Zdrahal

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Lyn controls chemotaxis and motility of CLL cells via phosphorylation of ROR1.

Z. Dave, O. Vondalova-Blanarova, S. Cada, P. Janovska, N. Zezula, M. Behal, K. Hanakova, S. R. Ganjani, P. Krejci, K. Gmöryöva, H. Peschelova, M. Smida, Z. Zdrahal, S. Pavlova, J. Kotaskova, , V. Bryja

This study shows Lyn phosphorylates ROR1, affecting its surface levels and migratory properties in CLL cells, linking BCR and ROR1 signaling.

bioRxiv · May 29, 2020Cancer Biology

RNF43 truncating mutations mediate a tumour suppressor-to-oncogene switch to drive niche-independent self-renewal in cancer

M. Spit, N. Fenderico, I. Jordens, T. Radaszkiewicz, R. G. H. Lindeboom, J. M. Bugter, L. Ootes, M. van Osch, E. Janssen, K. E. Boonekamp, K. Hanakova, D. Potesil, Z. Zdrahal, S. F. Boj, J. P. Medema, , M. M. Maurice

This study identifies RNF43 truncating mutations that switch from tumor suppressor to oncogene, enabling niche-independent self-renewal in cancer and resistance to anti-Wnt therapy.

bioRxiv · Sep 1, 2019Cancer Biology

Phosphorylation of multiple proteins involved in ciliogenesis by Tau Tubulin kinase 2

O. Bernatik, P. Pejskova, D. Vyslouzil, K. Hanakova, Z. Zdrahal, L. Cajanek

This study identifies multiple TTBK2 substrates and their phosphorylation sites, showing their role in ciliogenesis and revealing distinct phosphorylation motifs.

bioRxiv · Jun 19, 2019Cell Biology

Comparative phosphorylation map of Dishevelled3 (DVL3)

K. Hanakova, O. Bernatik, P. Ovesna, M. Kravec, M. Micka, M. Radsetoulal, D. Potesil, L. Cajanek, Z. Zdrahal, V. Bryja

The study compares DVL3 phosphorylation by eight kinases and identifies kinase-specific phosphorylation signatures.

bioRxiv · May 2, 2019Cell Biology