Author

S. R. Johnson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 2 Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Assay:electrophysiology· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

A. L. Tatler· 2 shared R. Middlewick· 2 shared A. Bullock· 1 shared A. E. John· 1 shared A. Habgood· 1 shared A. John· 1 shared A. P. Carreno· 1 shared A. Prabhat· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersPhysiology

A. L. Tatler

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Feeding Behavior Modifies the Circadian Variation in RR and QT intervals by Distinct Mechanisms in Mice

M. Ono, D. Burgess, S. R. Johnson, C. S. Elayi, K. A. Esser, T. S. Seward, C. A. Boychuk, R. A. Stalcup, A. P. Carreno, A. Prabhat, E. Schroder, B. P. Delisle

This study shows feeding behavior affects RR and QT interval rhythms in mice through distinct mechanisms, with RR intervals linked to autonomic signaling and QT intervals to core body temperature.

bioRxiv · Nov 2, 2023Physiology

Computational Scoring and Experimental Evaluation of Enzymes Generated by Neural Networks

S. R. Johnson, X. Fu, S. Viknander, C. Goldin, S. Monaco, A. Zelezniak, K. K. Yang

The paper evaluates computational metrics for predicting enzyme activity in sequences generated by three models and finds that existing metrics like sequence identity and AlphaFold2 scores are not predictive.

bioRxiv · Mar 4, 2023Biochemistry

Differential remodelling in small and large murine airways revealed by novel whole lung airway analysis.

A. L. Tatler, C. J. Philp, M. R. Hill, S. Cox, A. Bullock, A. Habgood, A. John, R. Middlewick, K. E. Stephenson, A. T. Goodwin, C. K. Billington, R. D. O'Dea, B. S. Brook, S. R. Johnson

The paper uses a new method to analyze whole lung airway sections in mice, revealing differential remodelling in small and large airways after allergen challenge.

bioRxiv · Jan 15, 2022Physiology

Lysyl oxidase-like 2 (LOXL2) is Increased in Asthma and Contributes to Asthmatic Airway Remodelling

J. Ramis, R. Middlewick, F. Pappalardo, J. T. Cairns, I. D. Stewart, A. E. John, S.-u. Naveed, R. Krishnan, S. Miller, D. E. Shaw, C. E. Brightling, L. Buttery, F. R. Rose, G. Jenkins, S. R. Johnson, A. L. Tatler

This study shows LOXL2 is increased in asthma and contributes to airway remodelling by enhancing TGFβ activation and ECM stiffness.

bioRxiv · Nov 16, 2020 · PreprintCell Biology