Author

C. E. Brightling

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1

Frequent Co-Authors

A. B. Tobin· 1 shared A. E. John· 1 shared A. G. Alharbi· 1 shared A. L. Tatler· 1 shared C. Donovan· 1 shared C. H. Wiegman· 1 shared D. E. Shaw· 1 shared D. Kaur· 1 shared

Activity by Year

2020-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperPharmacology & Toxicology

A. B. Tobin

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Lysyl oxidase-like 2 (LOXL2) is Increased in Asthma and Contributes to Asthmatic Airway Remodelling

J. Ramis, R. Middlewick, F. Pappalardo, J. T. Cairns, I. D. Stewart, A. E. John, S.-u. Naveed, R. Krishnan, S. Miller, D. E. Shaw, C. E. Brightling, L. Buttery, F. R. Rose, G. Jenkins, S. R. Johnson, A. L. Tatler

This study shows LOXL2 is increased in asthma and contributes to airway remodelling by enhancing TGFβ activation and ECM stiffness.

bioRxiv · Nov 16, 2020 · PreprintCell Biology

Pathophysiological regulation of lung function by the free fatty acid receptor FFA4

A. B. Tobin, R. Prihandoko, D. Kaur, C. H. Wiegman, E. Alvarez-Curto, C. Donovan, L. Chachi, T. Ulven, M. R. Tyas, E. Euston, Z. Dong, A. G. Alharbi, R. Kim, J. G. Lowe, P. M. Hansbro, , G. Milligan

This study shows that activating FFA4 reduces airway resistance in mouse models of inflammation and human lung tissue, suggesting it could be a therapeutic target for asthma and COPD.

bioRxiv · May 18, 2020Pharmacology & Toxicology