Author

K. A. Esser

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 8

Signature Assays, Organisms & Methods

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Approach:experimental assay· 7 Research Focus:cell type annotation· 5 Organism:mouse· 5 Assay:bulk RNA-seq· 3 Organism:human· 3 Research Focus:chromatin & epigenetic regulation· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2

Frequent Co-Authors

C. A. Wolff· 4 shared X. Zhang· 3 shared C. M. Douglas· 2 shared S. J. Hesketh· 2 shared Z. Huo· 2 shared A. Altintas· 1 shared A. Garnham· 1 shared A. J. Genders· 1 shared

Activity by Year

2020-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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4 shared papersPhysiology

C. A. Wolff

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Author profile →

8 papers

Recent·Most cited

Feeding Behavior Modifies the Circadian Variation in RR and QT intervals by Distinct Mechanisms in Mice

M. Ono, D. Burgess, S. R. Johnson, C. S. Elayi, K. A. Esser, T. S. Seward, C. A. Boychuk, R. A. Stalcup, A. P. Carreno, A. Prabhat, E. Schroder, B. P. Delisle

This study shows feeding behavior affects RR and QT interval rhythms in mice through distinct mechanisms, with RR intervals linked to autonomic signaling and QT intervals to core body temperature.

bioRxiv · Nov 2, 2023Physiology

Skeletal muscle BMAL1 is necessary for transcriptional adaptation of local and peripheral tissues in response to endurance exercise training.

M. R. Viggars, H. E. Berko, S. J. Hesketh, C. A. Wolff, M. A. Gutierrez Monreal, R. A. Martin, I. G. Jennings, Z. Huo, K. A. Esser

This study shows that BMAL1 in skeletal muscle is essential for transcriptional responses to exercise and peripheral tissue adaptations, with its loss leading to divergent transcriptomic and metabolomic changes and increased inflammation.

bioRxiv · Oct 13, 2023Physiology

Morning endurance training induces superior performance adaptations compared to afternoon training in mice

S. J. Hesketh, C. M. Douglas, X. Zhang, C. A. Wolff, C. L. Sexton, E. S. Nowicki, K. A. Esser

This study shows that morning endurance training in mice leads to better performance adaptations than afternoon training, despite lower training volumes.

bioRxiv · Sep 18, 2023Physiology

An Optimized Approach to Study Sub-Sarcomere Structure Utilizing Super-Resolution Microscopy with Secondary VHH Nanobodies

C. M. Douglas, J. E. Bird, D. Kopinke, K. A. Esser

This study develops a method to visualize sub-sarcomere structures using optimized super-resolution microscopy and VHH nanobodies, enabling precise protein localization analysis in skeletal muscle.

bioRxiv · Sep 7, 2022 · PreprintPhysiology

The Skeletal Muscle Circadian Clock Regulates Titin Splicing Through RBM20

L. Riley, X. Zhang, C. Douglas, J. Mijares, D. Hammers, C. A. Wolff, N. B. Wood, H. Olafson, P. Du, S. Labeit, M. J. Previs, E. T. Wang, K. A. Esser

This study shows that the skeletal muscle circadian clock regulates titin splicing via RBM20, affecting sarcomere length and function.

bioRxiv · May 27, 2021Physiology

Disrupted circadian core-clock oscillations in Type 2 Diabetes are linked to altered rhythmic mitochondrial metabolism

B. M. Gabriel, A. Altintas, J. A. B. Smith, L. Sardon Puig, X. Zhang, A. Linde Basse, R. C. Laker, H. Gao, Z. Liu, L. Dollet, J. T. Treebak, A. Zorzano, Z. Huo, M. Ryden, J. T. Lanner, , J. R. Zierath

bioRxiv · Feb 24, 2021Physiology

Exercise mitigates sleep-loss-induced changes in glucose tolerance, mitochondrial function, sarcoplasmic protein synthesis, and circadian rhythms.

N. J. Saner, M. J.-C. Lee, J. Kuang, N. W. Pitchford, G. D. Roach, A. Garnham, A. J. Genders, T. Stokes, E. A. Schroder, K. A. Esser, S. M. Phillips, D. J. Bishop, J. D. Bartlett

This study shows that high-intensity interval exercise mitigates sleep loss-induced impairments in glucose tolerance, mitochondrial function, sarcoplasmic protein synthesis, and circadian rhythms.

bioRxiv · Jun 21, 2020Physiology

Time of Day Dependent Effects of Contractile Activity on the Phase of the Skeletal Muscle Clock

D. Kemler, C. A. Wolff, K. A. Esser

This study shows that treadmill exercise at specific times of day shifts the skeletal muscle circadian clock phase, with contractions also inducing phase changes in an in-vitro model.

bioRxiv · Mar 5, 2020Physiology