Author

S. R. Polio

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 2 Assay:imaging· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

H. Parameswaran· 2 shared A. J. Crosby· 1 shared A. N. Kundu· 1 shared C. E. Dougan· 1 shared D. E. Aurien-Blajeni· 1 shared J. D. Schiffman· 1 shared J. W. Ruberti· 1 shared N. P. Birch· 1 shared

Activity by Year

2018-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersBioengineering

H. Parameswaran

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3 papers

Recent·Most cited

Stiffening of the Extracellular Matrix is a Sufficient Condition for AirwayHyperreactivity.

R. R. Jamieson, S. E. Stasiak, S. R. Polio, J. W. Ruberti, H. Parameswaran

This study shows that increasing airway extracellular matrix stiffness through collagen crosslinking leads to enhanced bronchoconstriction, suggesting matrix remodeling as a key driver of airway hyperreactivity in asthma.

bioRxiv · Jun 27, 2020Bioengineering

Extracellular matrix stiffness regulates force transmission pathways in multicellular ensembles of human airway smooth muscle cells.

S. R. Polio, S. Stasiak, R. Krishnan, H. Parameswaran

This study shows ECM stiffness regulates force transmission in human airway smooth muscle cell ensembles by switching between ECM and cell-cell force transmission pathways.

bioRxiv · Sep 28, 2018Bioengineering

Cross-Platform Mechanical Characterization of Lung Tissue

S. R. Polio, A. N. Kundu, C. E. Dougan, N. P. Birch, D. E. Aurien-Blajeni, J. D. Schiffman, A. J. Crosby, S. R. Peyton

This study compares mechanical characterization techniques to quantify lung tissue modulus, finding cavitation rheology provides microscale measurements on intact tissue with higher modulus values.

bioRxiv · May 16, 2018Bioengineering