Author

S. Rodriguez-Rosado

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Organism:mouse· 2 Assay:proteomics· 2 Approach:deep learning· 1 Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Basbaum· 2 shared B. K. Shoichet· 2 shared K. Bhardwaj· 2 shared A. A. Inoue· 1 shared A. Allikalt· 1 shared A. Ullrich· 1 shared B. Bottcher· 1 shared B. J. Bender· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersPharmacology & Toxicology

A. Basbaum

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2 papers

Recent·Most cited

Structure-Based Discovery of a NPFF1R Antagonist with Analgesic Activity

B. J. Bender, J. E. Pickett, J. Braz, H. J. Kang, S. Gahbauer, K. Bhardwaj, S. Rodriguez-Rosado, Y. Liu, M. Jain, A. Basbaum, B. L. Roth, B. K. Shoichet

This paper identifies a selective NPFF1R antagonist with analgesic properties, showing enhanced pain relief when combined with morphine and reduced side effects.

bioRxiv · Oct 25, 2023 · PreprintPharmacology & Toxicology

Discovery of a functionally selective serotonin 5-HT1A receptor agonist for the treatment of pain

A. Ullrich, J. Schneider, J. M. Braz, E. Neu, N. Staffen, M. Stanek, J. Blahova, T. Hove, T. Albert, A. Allikalt, S. Lober, K. Bhardwaj, S. Rodriguez-Rosado, E. A. Fink, T. Rasmussen, , P. Gmeiner

The paper identifies ST171, a selective 5-HT1A receptor agonist effective in pain models without sedation, and elucidates its mechanism through structural and computational analysis.

bioRxiv · Sep 11, 2023 · PreprintPharmacology & Toxicology