Author

H. J. Kang

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Plant Biology· 2 Biochemistry· 1 Biophysics· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Assay:proteomics· 4 Approach:biophysical modeling· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:drug response / drug discovery· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:chromatin & epigenetic regulation· 1 Assay:cryo-EM· 1

Frequent Co-Authors

B. L. Roth· 2 shared D. Choi· 2 shared A. B. Pinkerton· 1 shared A. Basbaum· 1 shared A. Martin-Gonzalez· 1 shared B. E. Krumm· 1 shared B. J. Bender· 1 shared B. K. Shoichet· 1 shared

Activity by Year

2018-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 11 mutual co-author links

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2 shared papersPharmacology & Toxicology

B. L. Roth

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

An RXLR effector targets ER-Golgi interface to induce ER stress and necrotic cell death

J. Kim, J. Kaleku, H. Kim, M. Kang, H. J. Kang, c. segonzac, J. Woo, E. Park, D. Choi

This study identifies Pc12, an RXLR effector from P. capsici, which induces necrotic cell death by disrupting ER-Golgi trafficking through interaction with Rab13-2.

bioRxiv · Dec 15, 2023Plant Biology

Structure-Based Discovery of a NPFF1R Antagonist with Analgesic Activity

B. J. Bender, J. E. Pickett, J. Braz, H. J. Kang, S. Gahbauer, K. Bhardwaj, S. Rodriguez-Rosado, Y. Liu, M. Jain, A. Basbaum, B. L. Roth, B. K. Shoichet

This paper identifies a selective NPFF1R antagonist with analgesic properties, showing enhanced pain relief when combined with morphine and reduced side effects.

bioRxiv · Oct 25, 2023 · PreprintPharmacology & Toxicology

Oomycete effector AVRblb2 targets cyclic nucleotide-gated channels through calcium sensors to suppress pattern-triggered immunity

S. Lee, J. H. Lee, H.-Y. Lee, H. J. Kang, Y.-E. Seo, D. Choi

This study identifies AVRblb2 as an effector that targets CNGC channels via CaM/CML proteins to suppress PTI in plants.

bioRxiv · Jan 18, 2023Plant Biology

Neurotensin receptor allosterism revealed in complex with a biased allosteric modulator

B. E. Krumm, J. F. DiBerto, R. H. J. Olsen, H. J. Kang, S. T. Slocum, S. Zhang, R. T. Strachan, L. M. Slosky, A. B. Pinkerton, L. S. Barak, M. G. Caron, T. Kenakin, B. L. Roth

This study reveals the cryoEM structures of NTSR1 with and without SBI-553, showing its biased allosteric modulation of G protein and β-Arrestin signaling.

bioRxiv · Dec 26, 2022 · PreprintBiophysics

Human CtIP forms a tetrameric dumbbell-shaped particle which binds and bridges complex DNA end structures for double-strand break repair

O. J. Wilkinson, A. Martin-Gonzalez, H. J. Kang, S. J. Northall, D. B. Wigley, F. Moreno-Herrero, M. S. Dillingham

This study shows human CtIP forms a tetramer that binds and bridges DNA ends, facilitating resection for double-strand break repair.

bioRxiv · Sep 5, 2018Biochemistry