The interferon/STAT1 signaling axis is a common feature of tumor-initiating cells in breast cancer
E. P. Souto, P. Gong, J. D. Landua, R. R. Srinivasan, A. Ganesan, L. E. Dobrolecki, S. C. Purdy, X. Pan, M. Zeosky, A. Chung, S. S. Yi, H. L. Ford, M. T. Lewis
The paper identifies an IFN/STAT1 transcriptional state in tumor-initiating cells (TIC) of breast cancer using single-cell RNA sequencing, showing it differs from bulk RNA-seq derived TIC signatures.
bioRxiv · Sep 15, 2023 · PreprintCancer Biology