A. Chung

Improving Inverse Folding models at Protein Stability Prediction without additional Training or Data

The paper improves protein stability prediction by modifying existing models with a self-derived term, enhancing their performance without additional training or data.

Single-cell and spatial atlas of steatotic liver-related hepatocellular carcinoma

This study characterizes the tumor microenvironment of steatotic liver-related hepatocellular carcinoma using single-cell and spatial transcriptomic analyses, identifying immunosuppressive features and Treg-CAF interactions linked to immunotherapy resistance.

Novel assay for endangered Hong Kong grouper (Epinephelus akaara) to assess eDNA shedding, decay, and population status

The paper develops a species-specific qPCR assay to detect endangered Hong Kong grouper eDNA in water samples, finding low shedding rates and rare occurrence.

ADAMTS7 promotes smooth muscle foam cell expansion in atherosclerosis

This study identifies ADAMTS7's role in promoting atherosclerosis by enhancing smooth muscle cell foam cell formation via an AP-1/PU.1/CD36 pathway.

Variable responses of individual species to tropical forest degradation

The study examines how individual species respond to tropical forest degradation, finding significant variation in responses across populations and surveys.

Liver cancer initiation is dependent on metabolic zonation but decoupled from premalignant clonal expansion

This study shows that liver cancer initiation depends on metabolic zonation but is not linked to premalignant clonal expansion.

Distinct resource utilization by introduced man-made grouper hybrid: an overlooked anthropogenic impact from a longstanding religious practise

This study analyzes the diet of a man-made hybrid grouper released into the wild through religious practices, finding it consumes different prey than native species and may impact marine ecosystems.

The interferon/STAT1 signaling axis is a common feature of tumor-initiating cells in breast cancer

The paper identifies an IFN/STAT1 transcriptional state in tumor-initiating cells (TIC) of breast cancer using single-cell RNA sequencing, showing it differs from bulk RNA-seq derived TIC signatures.

Vgamma9Vdelta2 T cells recognize butyrophilin 2A1 and 3A1 heteromers

The paper reveals that Vgamma9Vdelta2 T cells recognize BTN2A1 and BTN3A1 heteromers through dual epitope engagement, uncovering a new mechanism of immune activation.

Declining population sizes and loss of genetic diversity in commercial fishes: a simple method for a first diagnostic

The paper assesses genetic diversity loss in exploited fish species using COI markers and finds it aligns with theoretical predictions and fishing pressures.