Author

S. Scherer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Microbiology· 3 Biophysics· 1 Cancer Biology· 1 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell type annotation· 3 Assay:proteomics· 3 Approach:statistical model· 3 Organism:bacteria (other)· 2 Approach:deep learning· 2 Assay:DNA methylation· 2 Organism:E. coli· 2 Approach:experimental assay· 2

Frequent Co-Authors

K. Neuhaus· 4 shared Z. Ardern· 4 shared M. Kreitmeier· 3 shared B. Zehentner· 2 shared A. Bertotti· 1 shared A. C. O'Farrell· 1 shared A. L. Welm· 1 shared A. Lafferty· 1 shared

Activity by Year

2017-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

4 shared papersMicrobiology

K. Neuhaus

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Shadow ORFs illuminated: long overlapping genes in Pseudomonas aeruginosa are translated and under purifying selection

M. Kreitmeier, Z. Ardern, M. Abele, C. Ludwig, S. Scherer, K. Neuhaus

The paper identifies two long overlapping genes in Pseudomonas aeruginosa that are translated and under purifying selection, expanding understanding of prokaryotic genomic complexity.

bioRxiv · Feb 9, 2021 · PreprintEvolutionary Biology

Evidence for Numerous Embedded Antisense Overlapping Genes in Diverse E. coli Strains

B. Zehentner, Z. Ardern, M. Kreitmeier, S. Scherer, K. Neuhaus

The paper identifies numerous embedded antisense overlapping genes in E. coli strains using RNAseq and ribosome profiling, suggesting they may be functionally significant and underappreciated in genome annotation.

bioRxiv · Nov 18, 2020 · PreprintMicrobiology

Are Antisense Proteins in Prokaryotes Functional?

Z. Ardern, K. Neuhaus, S. Scherer

The paper investigates whether antisense proteins in prokaryotes are functional, finding evidence supporting their utility and suggesting they should be included in genome annotations.

bioRxiv · Feb 20, 2020Microbiology

Conservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts

X. Y. Woo, J. Giordano, A. Srivastava, Z.-M. Zhao, M. W. Lloyd, R. de Bruijn, Y.-S. Suh, R. Patidar, L. Chen, S. Scherer, M. Bailey, C.-H. Yang, E. Cortes-Sanchez, Y. Xi, J. Wang, , B. E Welm

This study shows that copy number profiles are conserved in patient-derived xenografts (PDXs) through engraftment and passaging, indicating minimal impact from the mouse host on tumor evolution.

bioRxiv · Dec 3, 2019Cancer Biology

A novel pH-regulated, unusual 603 bp overlapping protein coding gene pop is encoded antisense to ompA in Escherichia coli O157:H7 (EHEC)

B. Zehentner, Z. Ardern, M. Kreitmeier, S. Scherer, K. Neuhaus

The paper identifies a novel pH-regulated, antisense protein-coding gene overlapping ompA in E. coli O157:H7, showing translation and a pH-dependent phenotype.

bioRxiv · Nov 23, 2019Microbiology

Image processing techniques for high-resolution structure determination from badly ordered 2D crystals

N. Biyani, S. Scherer, R. D. Righetto, J. Kowal, M. Chami, H. Stahlberg

The paper develops image-processing algorithms to improve 3D structure determination from badly ordered 2D crystals, achieving resolution improvements to approximately 5 Å.

bioRxiv · Mar 3, 2017Biophysics