Author

M. W. Lloyd

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 4

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:clustering· 2 Assay:DNA methylation· 2 Organism:human· 2 Organism:mouse· 2

Frequent Co-Authors

A. Srivastava· 4 shared B. J. Sanderson· 3 shared A. L. Welm· 2 shared B. Davis-Dusenbery· 2 shared C. Frech· 2 shared C. J. Bult· 2 shared D. A. Dean· 2 shared J. H. Chuang· 2 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersCancer Biology

A. Srivastava

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Author profile →

4 papers

Recent·Most cited

Development and application of genetic ancestry reconstruction methods to study diversity of patient-derived models in the NCI PDXNet Consortium

B. J. Sanderson, P. Lott, K. Chiu, J. E. Quino, A. P. Vang, M. W. Lloyd, A. Srivastava, PDXNet Consortium, J. H. Chuang, L. G. Carvajal-Carmona

The paper develops a genetic ancestry pipeline to assess diversity in PDX models and finds overrepresentation of European ancestry models, highlighting gaps in minority representation for cancer research.

bioRxiv · Oct 24, 2022 · PreprintCancer Biology

A Genomically and Clinically Annotated Patient Derived Xenograft (PDX) Resource for Preclinical Research in Non-Small Cell Lung Cancer

X. Y. Woo, A. Srivastava, P. C. Mack, J. H. Graber, B. J. Sanderson, M. W. Lloyd, M. Chen, S. Domanskyi, R. Gandour-Edwards, R. A. Tsai, J. Keck, M. Cheng, M. Bundy, E. L. Jocoy, J. W. Riess, , C. J. Bult

The paper describes a collection of 79 genomically and clinically annotated lung cancer PDX models that retain patient tumor features and treatment responses, available through MMHCdb.

bioRxiv · Mar 6, 2022Cancer Biology

PDXNet Portal: Patient-Derived Xenograft model, data, workflow, and tool discovery

S. Koc, M. W. Lloyd, J. Grover, S. Seepo, S. Lakshmi Subramanian, M. Ray, C. Frech, J. DiGiovanna, P. Webster, S. Neuhauser, A. Srivastava, X. Yi Woo, B. J. Sanderson, B. White, P. Lott, , J. H. Chuang

The paper introduces the PDXNet Portal, a centralized resource for PDX models and data, offering analysis workflows and facilitating cancer research collaboration.

bioRxiv · Oct 15, 2021Cancer Biology

Conservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts

X. Y. Woo, J. Giordano, A. Srivastava, Z.-M. Zhao, M. W. Lloyd, R. de Bruijn, Y.-S. Suh, R. Patidar, L. Chen, S. Scherer, M. Bailey, C.-H. Yang, E. Cortes-Sanchez, Y. Xi, J. Wang, , B. E Welm

This study shows that copy number profiles are conserved in patient-derived xenografts (PDXs) through engraftment and passaging, indicating minimal impact from the mouse host on tumor evolution.

bioRxiv · Dec 3, 2019Cancer Biology