Author

S. Shanmugam

Texas Tech University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1 Microbiology· 1 Neuroscience· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:differential expression· 2 Assay:metagenomics· 2 Organism:mouse· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

A. Narayanan· 1 shared A. Rajaraman· 1 shared A. T Ambikan· 1 shared Brent R. KisbyiD· 1 shared C. Tellapragada· 1 shared D. Castano Mayan· 1 shared D. Thongadi Ramesh· 1 shared D.-G. Jo· 1 shared

Activity by Year

2021-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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1 shared paperImmunology

A. Narayanan

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

EFFECTS OF TOLL-LIKE RECEPTOR 3 - DEPENDENT IMMUNE ACTIVATION IN MICE ARE SEX- AND TISSUE - SPECIFIC: IMPLICATIONS FOR ALCOHOL USE DISORDER

Philip Antwi‐Adjei, S. Shanmugam, Brent R. Kisby, Igor Ponomarev

This study examines sex- and tissue-specific immune responses to TLR3 activation in mice, finding differential gene and protein expression profiles that may influence alcohol consumption behaviors.

bioRxiv · Apr 24, 2026 · PreprintNeuroscience

Absence of the bile acid enzyme CYP8B1 increases brain chenodeoxycholic acid and reduces neuronal excitotoxicity in mice

V. F. Monteiro-Cardoso, X. Y. Yeo, H.-G. Bae, D. Castano Mayan, M. Wehbe, S. Lee, K. Krishna-K, S. H. Baek, L. F. Palomera, S. Shanmugam, K. P. Sem, M. P. Parsons, M. R. Hayden, E. A. Liehn, S. Sajikumar, , R. R. Singaraja

This study shows that absence of CYP8B1 increases brain chenodeoxycholic acid (CDCA) levels, reducing neuronal excitotoxicity and stroke infarct area in mice.

bioRxiv · Dec 11, 2022 · PreprintPhysiology

Differential effects of carbon nanotube and graphene on the tomato rhizosphere microbiome

Y. You, P. Kerner, S. Shanmugam, M. V. Khodakovskaya

This study compares the effects of carbon nanotubes and graphene on tomato rhizosphere microbiomes, finding that CNTs increase microbial diversity and alter community functions more than graphene.

bioRxiv · Nov 10, 2022 · PreprintMicrobiology

Deciphering the role of mucosal immune responses and cervicovaginal microbiome in resistance to HIV infection in HIV-exposed seronegative (HESN) women

S. Munusamy Ponnan, K. Thiruvengadam, C. Tellapragada, A. T Ambikan, A. Narayanan, S. Kathirvel, J. Shankar, A. Rajaraman, M. Afsan Amanulla, D. Thongadi Ramesh, P. Selvamuthu, S. Shanmugam, M. Kailapuri Gangatharan, S. Swaminathan, V. Velu, , L. E. Hanna

This study identifies elevated antiviral cytokines, immunoglobulins, and specific immune cell subsets in HESN women, along with increased bacterial diversity and Gardnerella spp abundance in the cervicovaginal microbiome, suggesting protective mechanisms against HIV.

bioRxiv · May 7, 2021Immunology