BiochemistrybioRxiv
Insights into the ISG15 transfer cascade by the UBE1L activating enzyme
I. Wallace, K. Baek, J. R. Prabu…·K. N. Swatek
This study presents a cryo-EM structure of the UBE1L-UBE2L6 complex bound to ISG15, revealing mechanisms of ISG15 recognition and conjugation pathway specificity.
DOI 10.1038/s41467-023-43711-3