Author

S. Waddell

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. D'Halluin· 1 shared A. H. Roberts· 1 shared A. Meynert· 1 shared A. Rodgers· 1 shared C. W. Moon· 1 shared D. Barker· 1 shared D. Sproul· 1 shared D. Wilson· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperMicrobiology

A. D'Halluin

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

EfpA is required for re-growth of Mycobacterium tuberculosis following isoniazid exposure

A. H. Roberts, C. W. Moon, V. Faulkner, S. L. Kendall, S. Waddell, J. Bacon

This study shows that EfpA is essential for Mycobacterium tuberculosis to recover from isoniazid exposure, with efpA-repressed cultures unable to form viable colonies after 45 days.

bioRxiv · Aug 31, 2023 · PreprintMicrobiology

In vivo modelling of patient genetic heterogeneity identifies concurrent Wnt and PI3K activity as a potent driver of invasive cholangiocarcinoma growth.

N. Younger, M. Wilson, E. Jarman, A. Meynert, G. Grimes, K. Gournopanos, S. Waddell, P. Tennant, D. Wilson, R. Guest, S. Wigmore, J. C. Acosta, T. J. Kendall, M. Taylor, D. Sproul, , L. Boulter

This study identifies concurrent Wnt and PI3K activity as drivers of invasive cholangiocarcinoma growth and shows that their co-inhibition slows tumor growth in vivo.

bioRxiv · Jul 5, 2021 · PreprintCancer Biology

The Mycobacterium tuberculosis sRNA F6 modifies expression of essential chaperonins, GroEL2 and GroES

J. Houghton, A. Rodgers, G. Rose, A. D'Halluin, T. Kipkorir, D. Barker, S. Waddell, K. B. Arnvig

This study identifies the M. tuberculosis sRNA F6 as a regulator of chaperonin expression under starvation conditions, suggesting a role in long-term survival.

bioRxiv · Jul 15, 2020Microbiology