Author

S. X. Chen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:variant calling· 1 Research Focus:variant effect prediction· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

A. A. Patel· 1 shared A. H. Sims· 1 shared A. Pinto· 1 shared B. Wang· 1 shared C. Jain· 1 shared D. J. Azzam· 1 shared D. Kwon· 1 shared D. Y. Zhang· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperBioengineering

A. A. Patel

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Author profile →

2 papers

Recent·Most cited

LBH is a cancer stem cell- and metastasis-driving oncogene essential for WNT stem cell function in breast cancer

K. Garikapati, K. Ashad-Bishop, S. Hong, R. Qureshi, M. E. Rieger, L. E. Lindley, B. Wang, D. J. Azzam, M. Khanlari, M. Nadji, C. Jain, D. Kwon, Y. Ban, Z. Gao, S. X. Chen, , K. J. Briegel

This study identifies LBH as a key oncogene driving cancer stem cell function and metastasis in breast cancer through WNT pathway activation.

bioRxiv · Jan 29, 2021 · PreprintCancer Biology

Detecting and Quantitating Low Fraction DNA Variants with Low-Depth Sequencing

P. Song, S. X. Chen, Y. H. Yan, A. Pinto, L. Y. Cheng, P. Dai, A. A. Patel, D. Y. Zhang

This paper introduces mBDA, a method to detect low-frequency DNA variants with low-depth sequencing, and applies it to find tumor heterogeneity in melanoma samples.

bioRxiv · Apr 26, 2020 · PreprintBioengineering