Author

S. Y. Lunt

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Bioengineering· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Assay:metabolomics· 3 Organism:mouse· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:drug response / drug discovery· 2 Approach:genetic perturbation / CRISPR· 2 Organism:human· 2 Assay:proteomics· 2

Frequent Co-Authors

M. P. Ogrodzinski· 2 shared S. T. Teoh· 2 shared A. Aurora· 1 shared A. L. Raithel· 1 shared B. Borhan· 1 shared C. C. Cooper· 1 shared C. Jauset· 1 shared C. Riera Domingo· 1 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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2 shared papersCancer Biology

M. P. Ogrodzinski

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

The glutathione import system satisfies the Staphylococcus aureus nutrient sulfur requirement and promotes interspecies competition.

J. M. Lensmire, M. R. Wischer, L. M. Sosinski, E. Ensink, J. P. Dodson, J. C. Shook, P. C. Delekta, C. C. Cooper, D. Havlichek, M. H. Mulks, S. Y. Lunt, J. Ravi, N. D. Hammer

This study identifies a glutathione import system in Staphylococcus aureus that enables sulfur acquisition and competitive advantage over S. epidermidis.

bioRxiv · Oct 26, 2021Microbiology

Heterogeneity in PHGDH protein expression potentiates cancer cell dissemination and metastasis

M. Rossi, G. Doglioni, L. Bornes, D. Broekart, M. Planque, J. Fernandez-Garcia, G. Rinaldi, J. Van Elsen, D. Nittner, C. Jauset, F. Rizzollo, C. Riera Domingo, M. Orth, L. E. Dobrolecki, T. Van Brussel, , S.-M. Fendt

This study identifies PHGDH protein expression heterogeneity as a driver of breast cancer metastasis by altering metabolic pathways and promoting dissemination.

bioRxiv · Jan 24, 2021Cancer Biology

Metabolomic profiling of mouse mammary tumor derived cell lines reveals targeted therapy options for cancer subtypes

M. P. Ogrodzinski, S. Y. Lunt

The paper identifies metabolic pathway differences between two breast cancer subtypes using metabolomics and shows the feasibility of targeting these pathways with specific compounds.

Cellular Oncology · Jul 20, 2020Peer-reviewedCancer Biology

Targeting subtype-specific metabolic preferences in nucleotide biosynthesis inhibits tumor growth in a breast cancer model

M. P. Ogrodzinski, S. T. Teoh, S. Y. Lunt

bioRxiv · Apr 19, 2020Cancer Biology

Modulating cellular cytotoxicity and phototoxicity of fluorescent organic salts through counterion pairing

D. Broadwater, M. Bates, M. Jayaram, M. Young, J. He, A. L. Raithel, T. W. Hamann, W. Zhang, B. Borhan, R. R. Lunt, S. Y. Lunt

This paper develops a platform to independently control cytotoxicity and phototoxicity of fluorescent organic salts through counterion pairing for optoelectronic tuning.

bioRxiv · Aug 22, 2019Bioengineering