S. Yan

This study clones and expresses the pig ACE2 gene in a prokaryotic system, produces a polyclonal antibody, and confirms ACE2 expression across pig tissues.

This study identifies that combining RNA Polymerase I inhibitor CX-5461 with TOP1 inhibitor topotecan enhances DNA damage response and efficacy in high-grade serous ovarian cancer.

The paper introduces MMCL, a GPU-accelerated mesh-based Monte Carlo photon transport simulator, achieving up to 420x speedup over CPU-based methods.

This paper introduces a method to classify platelet aggregates by agonist type using convolutional neural networks trained on high-throughput imaging data.

This paper introduces NIPSS, a nanopore sequencing method for direct miRNA sequencing, demonstrating single-molecule resolution and potential applications in cancer diagnostics and therapeutics.

This study shows CX-5461, an RNA polymerase I inhibitor, enhances PARP inhibitor efficacy in HR-deficient HGSOC by inducing replication stress and DNA damage, overcoming resistance mechanisms.

ESCRT-III and Vps4 were reconstituted to generate ATP-dependent forces for membrane scission, confirming their role in membrane cutting.

The paper re-analyzes data from two studies on language prediction, proposing Bayesian surprise and surprisal as measures of anticipatory processing and finding gradient correlations with N400 amplitudes.