Author

P. B. Madhamshettiwar

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

K. J. Simpson· 2 shared K. M. Hannan· 2 shared R. B. Pearson· 2 shared R. D. Hannan· 2 shared A. J. George· 1 shared C. Cullinane· 1 shared C. Engel· 1 shared C. M. Gould· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersCell Biology

K. J. Simpson

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Author profile →

2 papers

Recent·Most cited

Nuclear stabilisation of p53 requires a functional nucleolar surveillance pathway

K. M. Hannan, P. Soo, M. S. Wong, J. K. Lee, N. Hein, M. Evers, K. D. Wysoke, T. D. Williams, C. Montellese, L. Smith, S. J. Al-Obaidi, L. Nunez-Villacis, P. Poh, M. Pavy, J.-S. He, , A. J. George

This study identifies the nucleolar surveillance pathway (NSP) as a central regulator of p53 stability, showing its role in integrating various cellular stresses and its potential as a therapeutic target in cancer.

bioRxiv · Jan 21, 2021 · PreprintCell Biology

Targeting RNA Polymerase I transcription synergises with TOP1 inhibition in potentiating the DNA damage response in high-grade serous ovarian cancer

S. Yan, P. B. Madhamshettiwar, K. J. Simpson, S. Ellis, J. Kang, C. Cullinane, K. E. Sheppard, K. M. Hannan, R. D. Hannan, E. Sanij, R. B. Pearson, K. T. Chan

This study identifies that combining RNA Polymerase I inhibitor CX-5461 with TOP1 inhibitor topotecan enhances DNA damage response and efficacy in high-grade serous ovarian cancer.

bioRxiv · Nov 20, 2019Cancer Biology