Author

S.-E. Nam

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

C. K. Yip· 2 shared J. E. Burke· 2 shared M. A. Parson· 2 shared M. L. Jenkins· 2 shared N. J. Harris· 2 shared U. Dalwadi· 2 shared B. E. Moeller· 1 shared E. Sheeky· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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2 shared papersBiochemistry

C. K. Yip

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2 papers

Recent·Most cited

Allosteric activation or inhibition of PI3Kγ mediated through conformational changes in the p110γ helical domain

N. J. Harris, M. L. Jenkins, S.-E. Nam, M. K. Rathinaswamy, M. A. Parson, H. Ranga-Prasad, U. Dalwadi, B. E. Moeller, E. Sheeky, S. D. Hansen, C. K. Yip, J. E. Burke

This study identifies the helical domain of p110γ as an allosteric regulator of PI3Kγ activity, showing distinct roles in p110γ-p84 and p110γ-p101 complexes through phosphorylation or nanobody binding.

bioRxiv · Apr 12, 2023Biochemistry

Biochemical insight into novel Rab-GEF activity of the mammalian TRAPPIII complex

N. J. Harris, M. L. Jenkins, U. Dalwadi, K. D. Fleming, S.-E. Nam, M. A. Parson, C. K. Yip, J. E. Burke

This study investigates the GEF activity of TRAPPIII and TRAPPII complexes toward Rab GTPases using biochemical and structural methods, revealing Rab specificity and membrane interaction mechanisms.

bioRxiv · Jun 1, 2021Biochemistry