Crystal structures and functional analysis of the ZnF5-WWE1-WWE2 region of PARP13/ZAP define a new mode of engaging poly(ADP-ribose)
J. R. A. Kuttiyatveetil, H. Soufari, M. Dasovich, I. R. Uribe, S.-J. Cheng, A. Leung, J. M. Pascal
The paper presents crystal structures of the ZnF5-WWE1-WWE2 region of PARP13 and shows it binds poly(ADP-ribose) through WWE2, revealing a new mode of recognition.
bioRxiv · Dec 15, 2021 · PreprintBiochemistry