Author

T. Tsukamoto

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Microbiology· 2 Biochemistry· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Assay:flow cytometry· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

A. G. Thomas· 1 shared A. K. Jayabalan· 1 shared A. Leung· 1 shared A. Vachiraarunwong· 1 shared B. Murphy· 1 shared B. S. Slusher· 1 shared G. Qiu· 1 shared H. Wanibuchi· 1 shared

Activity by Year

2017-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperBiochemistry

A. G. Thomas

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

A Novel Support Vector Machine-Based One-Day, Single-Dose Prediction Model of Genotoxic Hepatocarcinogenicity in Rats

M. Gi, S. Suzuki, M. Kanki, M. Yokohira, T. Tsukamoto, M. Fujioka, A. Vachiraarunwong, G. Qiu, R. Guo, H. Wanibuchi

This paper develops a support vector machine-based model to predict genotoxic hepatocarcinogens in rats using gene expression data from a single dose and day of exposure.

bioRxiv · Feb 19, 2024Pharmacology & Toxicology

High-throughput Activity Assay for Screening Inhibitors of the SARS-CoV-2 Mac1 Macrodomain

M. A. Dasovich, J. Zhuo, A. G. Thomas, J. A. Goodman, R. L. McPherson, A. K. Jayabalan, V. F. Busa, S.-J. Cheng, B. Murphy, K. R. Redinger, T. Tsukamoto, B. S. Slusher, J. Bosch, J. Wei, A. Leung

The paper develops a high-throughput assay for screening inhibitors of the SARS-CoV-2 Mac1 macrodomain and identifies dasatinib and dihydralazine as inhibitors with selectivity over human MacroD2.

bioRxiv · Oct 7, 2021Biochemistry

CXCR4-associated depletion of bone marrow CD34+ cells following CCR5-tropic HIV-1 infection of humanized NOD/SCID/JAK3null mice and partial protection of those cells by a promotor-targeting shRNA

T. Tsukamoto

This study shows that HIV-1 infection depletes bone marrow CD34+ cells in humanized mice via CXCR4, but a promoter-targeting shRNA protects these cells and reduces HIV replication.

bioRxiv · Jan 22, 2018Microbiology

Use Of RetroNectin In Studies Requiring In Vitro HIV Infection Of Human Hematopoietic Stem/Progenitor Cells

T. Tsukamoto, S. Okada

The paper demonstrates that RetroNectin enhances HIV infection of CD34+ hematopoietic stem/progenitor cells in vitro, enabling better study of HIV's effects on these cells.

bioRxiv · May 25, 2017Microbiology