J. Bosch

Broad diversity of human gut bacteria accessible via a traceable strain deposition system

The paper establishes a publicly available collection of 340 human gut bacterial strains, including 29 newly described species, and identifies plasmids and megaplasmids within these isolates.

Potent AMA1-specific human monoclonal antibody against P. vivax Pre-erythrocytic and Blood Stages

The paper isolates a human monoclonal antibody that targets Plasmodium vivax AMA1, blocking both pre-erythrocytic and blood stage infections.

The Major Histocompatibility Complex modulates Batrachochytrium dendrobatidis and Ranavirus infections in three amphibian species

The paper examines the relationship between MHC diversity and infection status in three amphibian species exposed to Bd and Rv, finding associations between MHC alleles and infection intensity.

Naturally acquired and Vaccine-induced Human Monoclonal Antibodies to Plasmodium vivax Duffy Binding Protein Inhibit Invasion of Plasmodium knowlesi (PvDBPOR) Transgenic Parasites

This paper evaluates the invasion inhibition of Plasmodium knowlesi transgenic parasites expressing PvDBP by naturally acquired and vaccine-induced human monoclonal antibodies, finding additive and antagonistic effects in combinations.

High-throughput Activity Assay for Screening Inhibitors of the SARS-CoV-2 Mac1 Macrodomain

The paper develops a high-throughput assay for screening inhibitors of the SARS-CoV-2 Mac1 macrodomain and identifies dasatinib and dihydralazine as inhibitors with selectivity over human MacroD2.

Development of Small Molecule Inhibitors Targeting PBX1 Transcription Signaling as a Novel Cancer Therapeutic Strategy

This study develops small molecule inhibitors targeting PBX1 transcription signaling, showing they suppress cancer cell growth and re-sensitize resistant tumors.

Performance and impact of using a rapid molecular test to detect Chlamydia trachomatis and Neisseria gonorrhoeae in women suspected of having pelvic inflammatory disease

This study evaluates the prevalence of CT/NG infections in PID-suspected women and assesses the performance of a rapid molecular test compared to standard methods.