B. Murphy

Intraperitoneal activation of myeloid cells clears ascites and reveals IL27-dependent regression of metastatic ovarian cancer

The paper shows that intraperitoneal administration of β-glucan and IFNγ clears ascites and induces IL27-dependent tumor regression in metastatic ovarian cancer models.

High-throughput Activity Assay for Screening Inhibitors of the SARS-CoV-2 Mac1 Macrodomain

The paper develops a high-throughput assay for screening inhibitors of the SARS-CoV-2 Mac1 macrodomain and identifies dasatinib and dihydralazine as inhibitors with selectivity over human MacroD2.

Capturing site-to-site variability through Hierarchical Bayesian calibration of a process-based dynamic vegetation model

This paper introduces a hierarchical Bayesian calibration method for dynamic vegetation models, showing it improves prediction accuracy by accounting for site-to-site parameter variability.

Deep learning identifies pathological abnormalities predictive of graft loss in kidney transplant biopsies

This paper develops a deep learning model to quantify pathological features in kidney transplant biopsies, showing improved prediction of graft loss compared to clinical and Banff scores.

Collagen fibre-mediated mechanical damage increases calcification of bovine pericardium for use in bioprosthetic heart valves

This study shows mechanical damage increases calcification in bovine pericardium used for bioprosthetic heart valves, with calcification varying spatially based on damage levels.

A classification of functional pitcher types in Nepenthes (Nepenthaceae).

This paper classifies Nepenthes species into 12 functional pitcher types based on nutrient capture syndromes and maps their evolution on a phylogenomic tree.

A phylogenomic analysis of Nepenthes (Nepenthaceae)

This study uses high-throughput sequencing to analyze the phylogeny of Nepenthes species, confirming some clades and highlighting inconsistencies in others.