An extended Tudor domain within Vreteno interconnects Gtsf1L and Ago3 for piRNA biogenesis in Bombyx mori
Alfred W. Bronkhorst, Chop Yan Lee, Martin M. Möckel, Sabine Ruegenberg, António Miguel de Jesus Domingues, Shéraz Sadouki, Tetsutaro Sumiyoshi, Mikiko C. Siomi, Lukas S. Stelzl, Katja Luck, René F. Ketting
This study identifies a novel interaction between BmGtsf1L and BmVreteno's eTudor domain that facilitates piRNA biogenesis in Bombyx mori by connecting piRNA-loaded BmAgo3 and Gtsf1L.
bioRxiv · Mar 23, 2023 · PreprintMolecular Biology