Author

Sachie Ikegami

University of Chicago

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Alexis V. StutzmaniD· 1 shared Arghajit Pyne· 1 shared Atsuki EniD· 1 shared Briana Thomas· 1 shared Brigitte LaForestiD· 1 shared Hanumakumar Bogireddi· 1 shared Ivan P. G. MoskowitziD· 1 shared Kohta IkegamiiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperMolecular Biology

Alexis V. StutzmanORCID

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2 papers

Recent·Most cited

Digest before Ingest: Early Recruitment of Membrane-bound DNaseX to Phagocytic Cups in Macrophages

Arghajit Pyne, Vivek Pandey, Subhankar Kundu, Sachie Ikegami, Xuefeng Wang

The paper identifies early membrane-bound DNaseX activity at phagocytic cups in macrophages, enabling extracellular DNA degradation without internalization.

bioRxiv · Jul 16, 2026 · PreprintCell Biology

Pervasive nuclear envelope ruptures precede ECM signaling and disease onset without activating cGAS-STING in Lamin-cardiomyopathy mice

Atsuki En, Hanumakumar Bogireddi, Briana Thomas, Alexis V. Stutzman, Sachie Ikegami, Brigitte LaForest, Omar Almakki, Peter Pytel, Ivan P. G. Moskowitz, Kohta Ikegami

The paper shows that NE ruptures occur before ECM signaling and disease in Lamin-cardiomyopathy mice without activating cGAS-STING.

Cell Reports · May 29, 2024Peer-reviewedMolecular Biology