Author

Saha, Kusumika

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Neuroscience· 1

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1 Approach:statistical model· 1

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Andrew L. CroxfordiD· 1 shared Burkhard BecheriD· 1 shared Daqian Sun· 1 shared Dennis W. DicksoniD· 1 shared Deyou ZhengiD· 1 shared E. Richard StanleyiD· 1 shared Eun Su ParkiD· 1 shared Fabrizio BiundoiD· 1 shared

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2019-2019 · peak 1/yr

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1 shared paperNeuroscience

Andrew L. CroxfordORCID

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1 paper

Recent·Most cited

Microglial homeostasis requires balanced CSF-1/CSF-2 receptor signaling

Violeta Chiţu, Fabrizio Biundo, Gabriel G. L. Shlager, Eun Su Park, Ping Wang, Maria E. Gulinello, Şölen Gökhan, Harmony C. Ketchum, Saha, Kusumika, Michael A. Deture, Dennis W. Dickson, Zbignew K. Wszolek, Deyou Zheng, Andrew L. Croxford, Burkhard Becher, , E. Richard Stanley

This study shows that reducing CSF-2 in Csf1r+/- mice rescues behavioral and histopathological deficits in ALSP by preventing microgliosis and transcriptomic changes, suggesting CSF-2 as a therapeutic target.

bioRxiv · Dec 23, 2019Neuroscience