Author

Harmony C. Ketchum

Albert Einstein College of Medicine

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Organism:human· 1

Frequent Co-Authors

Dennis W. DicksoniD· 2 shared E. Richard StanleyiD· 2 shared Fabrizio BiundoiD· 2 shared Gabriel G. L. Shlager· 2 shared Michael A. DetureiD· 2 shared Violeta ChiţuiD· 2 shared Zbignew K. Wszolek· 2 shared Andrea CurtabbiiD· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersNeuroscience

Dennis W. DicksonORCID

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Author profile →

3 papers

Recent·Most cited

TET3 regulates cellular terminal differentiation at the metabolic level

Isabel Mulet, Carmen Grueso-Cortina, Mireia Cortés-Cano, Daniela Gerovska D, Guangming Wu, Stefania Alexandra Iakab, Daniel Jiménez-Blasco, Andrea Curtabbi, Pablo Hernansanz‐Agustín, Harmony C. Ketchum, Israel Manjarrés-Raza, Frank Thomas Wunderlich, Juan Pedro Bolaños, Meelad M. Dawlaty, Carsten Hopf, , Natàlia Tàpia

This study shows TET3 regulates terminal differentiation by affecting mitochondrial metabolic maturation and oxidative phosphorylation in intestinal epithelial cells.

Nature Communications · Nov 18, 2024Peer-reviewedDevelopmental Biology

Granulocyte Colony Stimulating Factor causes cerebellar deficits and anxiety in a mouse model of CSF-1 receptor-related leukoencephalopathy

Fabrizio Biundo, Violeta Chiţu, Jaafar O. Tindi, Nesha S. Burghardt, Gabriel G. L. Shlager, Harmony C. Ketchum, Michael A. Deture, Dennis W. Dickson, Zbignew K. Wszolek, Kamran Khodakhah, E. Richard Stanley

This study shows that reducing Csf3 in Csf1r+/- mice improves anxiety, motor coordination, and social interaction but not cognitive deficits, and reduces microglial activation in the cerebellum.

bioRxiv · Feb 21, 2022 · PreprintNeuroscience

Microglial homeostasis requires balanced CSF-1/CSF-2 receptor signaling

Violeta Chiţu, Fabrizio Biundo, Gabriel G. L. Shlager, Eun Su Park, Ping Wang, Maria E. Gulinello, Şölen Gökhan, Harmony C. Ketchum, Saha, Kusumika, Michael A. Deture, Dennis W. Dickson, Zbignew K. Wszolek, Deyou Zheng, Andrew L. Croxford, Burkhard Becher, , E. Richard Stanley

This study shows that reducing CSF-2 in Csf1r+/- mice rescues behavioral and histopathological deficits in ALSP by preventing microgliosis and transcriptomic changes, suggesting CSF-2 as a therapeutic target.

bioRxiv · Dec 23, 2019Neuroscience