Non-apoptotic death of the C. elegans linker cell is primed by MYRF-1 activation of pqn-41/polyQ
Olya Yarychkivska, Simin Liu, Lauren Bayer Horowitz, Shiloh Newland, Peipei Wu, Saiya Mittal, Shogo Tamura, Tetiana Novosolova, David Faulkner Ritter, Yun Lu, Sevinç Ercan, Christopher M. Hammell, Shai Shaham
The paper identifies MYRF-1 as a regulator of non-apoptotic linker cell death in C. elegans, showing its role in priming death through activation of pqn-41/polyQ.
bioRxiv · Dec 11, 2025 · PreprintCell Biology