Author

Sam Macklin-Isquierdo

University of Arizona

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Organism:Drosophila· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Christopher J. DonnellyiD· 1 shared Daniela C. ZarnescuiD· 1 shared Danielle de Paula MoreiraiD· 1 shared Dominic L. JulianiD· 1 shared Eric B. AlsopiD· 1 shared Erik M. LehmkuhliD· 1 shared Ileana LorenziniiD· 1 shared Kendall R. Van Keuren‐JenseniD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperNeuroscience

Christopher J. DonnellyORCID

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1 paper

Recent·Most cited

ADAR2-Mediated RNA Editing Promotes TDP-43 Nuclear Export and Alters RNA Binding

Stephen R. Moore, Dominic L. Julian, Eric B. Alsop, Lauren M. Gittings, Ileana Lorenzini, Michael McMillan, Sam Macklin-Isquierdo, Erik M. Lehmkuhl, Petr Kaláb, Danielle de Paula Moreira, Lindsey R. Hayes, Christopher J. Donnelly, Sami J. Barmada, Daniela C. Zarnescu, Kendall R. Van Keuren‐Jensen, Rita Sattler

This study shows ADAR2-mediated RNA editing promotes TDP-43 nuclear export and alters its RNA binding, contributing to neurodegenerative disease mechanisms.

bioRxiv · Jun 25, 2026 · PreprintNeuroscience